Sulfamethoxazole hydroxylamine

Specifications / Handling

More Information
Product Details
Synonyms	Sulfamethoxazole N4-hydroxylamine; SMX-HA; SMX-NHOH; NSC 665547; 4-(Hydroxyamino)-N-(5-methyl-3-isoxazolyl)benzenesulfonamide
Product Type	Chemical
Properties
Formula	C₁₀H₁₁N₃O₄S
MW	269.28
CAS	114438-33-4
Source/Host Chemicals	Synthetic
Purity Chemicals	≥98% (HPLC)
Appearance	Off-white powder.
Solubility	Soluble in methanol or DMSO. Sligthly soluble in water.
Identity	Determined by NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	MJAMPGKHIZXVFJ-UHFFFAOYSA-N
Smiles	CC1=CC(NS(=O)(=O)C2=CC=C(NO)C=C2)=NO1
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Keep cool and dry. Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Metabolite of sulfamethoxazole, a sulfonamide bacteriostatic antibiotic. Has been shown to be an important component in sulfonamide hypersensitivity reactions and has been implicated in sulfonamide-mediated immunomodulatory effects. Shown to induce lymphocyte toxicity and suppression of proliferation. Compound can be used as analytical reference material.

Product References

(1) J.S. Leeder, et al.; Biochem. Pharmacol. 41, 575 (1991) | (2) A.E. Cribb & S.P. Spielberg; Clin. Pharmacol. Ther. 51, 522 (1992) | (3) M.J. Rieder, et al.; Int. J. Immunopharmacol. 14, 1175 (1992) | (4) D.A. Hess, et al.; J. Pharmacol. Exp. Ther. 281, 540 (1997) | (5) D.A. Hess, et al.; FASEB J. 13, 1688 (1999) | (6) D.A. Hess, et al.; FASEB J. 15, 1855 (2001)

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