Chemodex

Saroglitazar magnesium

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CDX-S0378-M0055 mgCHF 142.00
CDX-S0378-M02525 mgCHF 567.00
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Product Details
Synonyms (αS)-α-Ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]benzenepropanoic acid Magnesium; (s)-2-Ethoxy-3-(4-(2-(2-methyl-5-(4-(methylthio)phenyl)-1H-pyrrol-1-yl)ethoxy)phenyl)propanoic acid Magnesium
Product Type Chemical
Properties
Formula C50H56MgN2O8S2
MW 901.44
CAS 1639792-20-3
Source/Host Chemicals Synthetic
Purity Chemicals ≥98% (HPLC)
Appearance White to beige powder.
Solubility Soluble in DMSO (2mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturer's product datasheet.

InChi Key UJYFZCVPOSZDMK-YPPDDXJESA-L
Smiles CC1=CC=C(C2=CC=C(SC)C=C2)N1CCOC(C=C3)=CC=C3CC4[O]([Mg+2]([O-]C4=O)([O-]C5=O)[O](C5CC6=CC=C(OCCN7C(C8=CC=C(SC)C=C8)=CC=C7C)C=C6)CC)CC
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet Download PDF
Description
Saroglitazar is a potent and selective PPARα/γ (peroxisome proliferator-activated receptor) agonist that exhibits lipid-lowering, antidiabetic and insulin-sensitizing effects. It also shows neuroprotective properties.
Product References
(1) R.H. Jani, et al.; Clin. Drug Investig. 33, 809 (2013) | (2) M.R. Jain, et al.; Pharmacol. Res. Perspect. 3, e00136 (2015) | (3) D. Kumar, et al.; Eur. J. Pharmacol. 822, 32 (2018) | (4) M.R. Jain, et al.; Liver Int. 38, 1084 (2018) | (5) R.N. Dharavath, et al.; Life Sci. 271, 119191 (2021) | (6) S. Francque; Hepatology 74, 1730 (2021) | (7) G. Sandeep Ganesh, et al.; ACS Chem. Neurosci. 14, 3444 (2023) | (8) D. Ezhilarasan; Metabolism 155, 155912 (2024) (Review)
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