Tyramine

CHF 31.00
In stock
CDX-T0168-G0055 gCHF 31.00
CDX-T0168-G02525 gCHF 80.00
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Product Details
Synonyms 2-(4-Hydroxyphenyl)ethylamine; 4-(2-Aminoethyl)phenol; 4-Hydroxyphenethylamine; NSC 249188; p-Tyramine; Uteramine
Product Type Chemical
Properties
Formula

C8H11NO

MW 137.2
CAS 51-67-2
Source/Host Chemicals Synthetic
Purity Chemicals ≥98% (NMR)
Appearance White to off-white powder.
Solubility Soluble in DMSO, methanol or ethanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key DZGWFCGJZKJUFP-UHFFFAOYSA-N
Smiles OC1=CC=C(CCN)C=C1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
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Product Specification Sheet
Datasheet Download PDF

Tyramine is a naturally-occurring trace amine derived from the amino acid tyrosine that is produced endogenously or can be obtained from certain foods. Tyramine acts as a catecholamine releasing agent. It is unable to cross the blood-brain barrier, resulting in only non-psychoactive peripheral sympathomimetic effects following ingestion. Acts as a adrenergic and activates trace amine-associated receptor 1. Tyramine also inhibits the release of norepinephrine and dopamine. It is metabolized by monoamine oxidase A. Primarily used as an intermediate in the manufacture of pharmaceutical and agrochemical products.

Product References

(1) A.J. Gross & I.W. Sizer; J. Biol. Chem.. 234, 1611 (1959) | (2) F. Sjoeqvist; Proc. R. Soc. Med. 58, 967 (1965) | (3) M. Da Prada, et al.; J. Neural. Transm. Suppl. 26, 31 (1988) | (4) R.B. Rothman, et al.; Science 39, 32 (2001) | (5) R. Zucchi, et al.; Br. J. Pharmacol. 149, 967 (2006) | (6) E.A. Reese, et al.; J. Pharmacol. Exp. Therap. 321, 178 (2007) | (7) J.J. Maguire, et al.; Pharmacol. Rev. 61,1 (2009)

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