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Chemodex
trans-4-Hydroxy-L-proline
54
CHF
CHF 54.00
In stock
CDX-T0254-G02525 gCHF 54.00
CDX-T0254-G100100 gCHF 162.00
| Product Details | |
|---|---|
| Synonyms | (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid; Hyp; (S)-(-)-trans-4-Hydroxyproline; 4(R)-Hydroxy-2(S)-pyrrolidinecarboxylic acid; NSC 46704; H-Hyp-OH; L-Hydroxypyroline |
| Product Type | Chemical |
| Properties | |
| Formula |
C5H9NO3 |
| MW | 131.13 |
| CAS | 51-35-4 |
| Purity Chemicals | ≥99% (TLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in water. |
| Identity | Determined by IR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | PMMYEEVYMWASQN-SYPWQXSBSA-N |
| Smiles | O[C@H]1CN[C@H](C(O)=O)C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Trans-4-Hydroxy-L-proline is a non-essential amino acid and a natural constituent of animal structural proteins such as collagen and elastin. It is commonly used as a chiral building block in the organic synthesis of various compounds, such as neuroexcitatory kainoids and antifungal echinocandins. It has been found in many bacterial secondary metabolites, including echinocandins.
Product References
(1) P. Remuzon, et al.; Tetrahedron 44, 13803 (1996) | (2) M.J. Blanco & F.J. Sardina; J. Org. Chem. 61, 4748 (1996) | (3) J.E. Baldwin, et al.; Bioorg. Med. Chem. Lett. 10, 1927 (2000) | (4) J.F. Poisson, et al.; J. Org. Chem. 70, 10860 (2005) | (5) G. Cremonesi, et al.; J. Org. Chem. 75, 2010 (2010)