Chemodex

Thymolphthalein

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Product Details
Synonyms 3,3-Bis(4-hydroxy-5-isopropyl-2-methylphenyl)isobenzofuran-1(3H)-one; 5?,5??-Diisopropyl-2?,2??-dimethylphenolphthalein; ; NSC 2186
Product Type Chemical
Properties
Formula C28H30O4
MW 430.54
CAS 125-20-2
Source/Host Chemicals Synthetic
Purity Chemicals ≥99% (HPLC)
Appearance White, faint beige powder or crystals.
Solubility Soluble in DMSO or EtOH (1mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key LDKDGDIWEUUXSH-UHFFFAOYSA-N
Smiles O=C1C2=CC=CC=C2C(C3=C(C)C=C(O)C(C(C)C)=C3)(C4=C(C)C=C(O)C(C(C)C)=C4)O1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +20°C
Handling Advice Keep under inert gas.
Very hygroscopic.
Use/Stability Stable for at least 2 years after receipt when stored at RT.
Documents
Product Specification Sheet
Datasheet Download PDF
Description
Thymolphthalein is a phthalein dye used as an acid-base (pH) indicator. It changes color depending on the pH of the solution. The pH transition range is from < 9.3 (colorless), 9.3-10.5 (light blue) to > 10.5 (deep blue). Spectral Data: λmax (UV-Vis): 590-598nm (0.1M NaOH). Specific Absorbance (E 1%/1cm): >750 @λmax. Can be used as a building block to synthesize Thymolphthalein monophosphate which is used as a substrate in enzymatic assays (e.g. alkaline phosphatase, ALP) and is used in clinical diagnostics, forensic tests and enzyme kinetics.
Product References
(1) M. Mohamed, et al.; Can. J. Chem. 57, 1294 (1979) | (2) T. Lin, et al.; Chem. Commun. (Camb) 59, 12986 (2023)
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