Chemodex

N-Undecanoyl-L-homoserine lactone

CHF 95.00
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CDX-U0026-M01010 mgCHF 95.00
CDX-U0026-M05050 mgCHF 285.00
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Product Details
Synonyms C11-L-HSL; C11-HSL; N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-undecanamide
Product Type Chemical
Properties
Formula

C15H27NO3

MW 269.39
CAS 216596-71-3
Source/Host Chemicals Synthetic
Purity Chemicals ≥97% (HPLC)
Appearance White solid.
Solubility Soluble in chloroform, DMSO (10mg/ml) or DMF (10mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key YAWJNUREPGJHSG-ZDUSSCGKSA-N
Smiles O=C1[C@@H](NC(CCCCCCCCCC)=O)CCO1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
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Product Specification Sheet
Datasheet Download PDF
Description

N-Undecanoyl-L-homoserine lactone lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. It appears later than shorter acyl chain AHLs in developing biofilms and, like other long chain AHLs, stimulates bacterial growth. C11-HSL possesses a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in P. aeruginosa strains.

Product References

(1) S.R. Chhabra, et al.; J. Med. Chem. 46, 97 (2003) | (2) C.F. Sio, et al.; Infect. Immun. 74, 1673 (2006) | (3) K.-G. Chan, et al.; BMC Microbiol. 11, 51 (2011) | (4) N. Singh, et al.; Virulence 8, 275 (2017)

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