|Synonyms||(6RS,7RS)-4,5,6,7-Tetrahydro-7-hydroxy-6-[(1-methylethyl) amino]imidazo[ 4,5,1-jk]benzazepin-2(1H)-one hydrochloride; Zilmax|
|Formula||C14H19N3O2 . HCl|
|Purity Chemicals||≥97% (HPLC)|
|Appearance||White to off-white powder.|
|Solubility||Soluble in water. Slightly soluble in methanol.|
|Identity||Determined by NMR.|
|Declaration||Manufactured by Chemodex.|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
Keep cool and dry.
Protect from light and moisture.
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
Synthetic β2-adrenoreceptor agonist that binds with the muscle β-adrenoreceptors, leading to the activation of protein kinase A, an enzyme responsible for changes in protein synthesis and degradation, in particular in skeletal muscles. Due to its partial activity towards β1-adrenoreceptors, has also the potential to affect cardiac muscle. In consequence, application of zilpaterol leads to preferential induction of fast glycolytic fibre types over slow oxidative fibre types resulting in enhanced growth efficiency and carcass leanness. Used as a veterinary drug in cattle to enhance growth performance in several countries.
(1) B. Bocca, et al.; J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 783, 141 (2003) | (2) C.P. Birkelo; Vet. Clin. North Am. Food Anim. Pract. 19, 599 (2003) (Review) | (3) K.C. Verhoeckx, et al.; J. Vet. Pharmacol. Ther. 28, 531 (2005) | (4) J.L. Montgomery, et al.; J. Anim. Sci. 87, 1374 (2009) | (5) J.M. Leheska, et al.; J. Anim. Sci. 87, 1384 (2009) | (6) C. Kern, et al.; J. Med. Chem. 52, 1773 (2009) | (7) T.J. Centner, et al.; J. Anim. Sci. 92, 4234 (2014) (Review) | (8) C.L. Van Bibber-Krueger, et al.; J. Anim. Sci. 93, 2419 (2015)