ZnAF-1F DA Solution

Specifications / Handling

More Information
Product Details
Synonyms	5-({2-[Bis(2-pyridinylmethyl)amino]ethyl}amino)-2-(2,7-difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid diacetate
Product Type	Chemical
Properties
Formula	C₃₈H₃₀F₂N₄O₇
MW	692.66
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥95% (HPCE)
Appearance	Liquid.
Solubility	Soluble in DMSO.
Concentration	5mM in DMSO (1mg in 0.29ml DMSO)
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	LPSDYSDKFVFVIH-UHFFFAOYSA-N
Smiles	CC(=O)OC1=CC2=C(C=C1F)C1(OC(=O)C3=C1C=CC(NCCN(CC1=CC=CC=N1)CC1=NC=CC=C1)=C3)C1=CC(F)=C(OC(C)=O)C=C1O2
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Keep cool and dry. Protect from light.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

For application to living cells, the diacetyl derivative of ZnAF-1F, ZnAF-1F DA, was synthesized. ZnAF-1F DA can permeate through the cell membrane, and is hydrolyzed by esterase in the cytosol to yield ZnAF-1F, which is retained in the cells. ZnAF-1F DA has been used to measure the changes of intracellular Zn2+ in cultured cells and hippocampal slices. Spectral data: λex 492nm; λem 514nm in PBS.

Product References

(1) S. Ueno, et al.; J. Cell Biol. 158, 215 (2002) | (2) T. Hirano, et al.; JACS 124, 6555 (2002)

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