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Chemodex
ZnAF-2F DA Solution
530
CHF
CHF 530.00
In stock
CDX-Z0512-M0011 mgCHF 530.00
| Product Details | |
|---|---|
| Synonyms | 6-{2-[Bis(2-pyridylmethyl)amino]ethylamino}-2′,7′-difluorofluorescein diacetate |
| Product Type | Chemical |
| Properties | |
| Formula | C38H30F2N4O7 |
| MW | 692.66 |
| CAS | 443302-10-1 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥95% (HPCE) |
| Appearance | Liquid. |
| Solubility | Soluble in DMSO. |
| Concentration | 5mM in DMSO (1mg in 0.29ml DMSO) |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | WACIJZVSTOSGHJ-UHFFFAOYSA-N |
| Smiles | CC(=O)OC1=CC2=C(C=C1F)C1(OC(=O)C3=C1C=C(NCCN(CC1=CC=CC=N1)CC1=NC=CC=C1)C=C3)C1=CC(F)=C(OC(C)=O)C=C1O2 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
For application to living cells, the diacetyl derivative of ZnAF-2F, ZnAF-2F DA, was synthesized. ZnAF-2F DA can permeate through the cell membrane, and is hydrolyzed by esterase in the cytosol to yield ZnAF-2F, which is retained in the cells. Using ZnAF-2F DA we could measure the changes of intracellular Zn2+ in cultured cells and hippocampal slices. Spectral data: λex 492nm; λem 515nm in PBS.
Product References
(1) S. Ueno, et al.; J. Cell Biol. 158, 215 (2002) | (2) T. Hirano, et al.; JACS 124, 6555 (2002)
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