CD160 (human):Fc (human) (rec.)

CHF 420.00
In stock
CHI-HF-210CD160-C100100 µgCHF 420.00
More Information
Product Details
Synonyms Natural Killer Cell Receptor BY55; NK28; NK1
Product Type Protein
Properties
Source/Host CHO cells
Sequence

The extracellular domain of human CD160 (aa 27-159) is fused to the N-terminus of the Fc region of human IgG1.

Crossreactivity Human
Biological Activity

Measured by its binding ability in a functional ELISA.

Purity ≥98% (SDS-PAGE)
Endotoxin Content <0.06EU/μg protein (LAL test; Lonza).
Reconstitution Reconstitute with 100 µl sterile water.
Add 1X PBS to the desired protein concentration.
Formulation Lyophilized from 0.2μm-filtered solution in PBS.
Protein Negative Control

Fc (human) IgG1 Control (rec.)

Other Product Data

NCBI reference NP_008984.1: CD160 (human)

Declaration Manufactured by Chimerigen.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. CD160-Fc fusion protein targets a novel costimulatory pathway and prolongs allograft survival.

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