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Chimerigen
Fc (human) IgG1 Control (rec.) (non-lytic)
390
CHF
CHF 390.00
In stock
CHI-HF-220IG1-C100100 µgCHF 390.00
| Product Details | |
|---|---|
| Product Type | Protein |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence |
Human IgG Fc region (aa 100-330) containing the hinge sequence. |
| Crossreactivity | Human |
| MW | ~25-35kDa (SDS-PAGE) |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <1EU/mg purified protein (LAL test; Lonza). |
| Reconstitution | Reconstitute with 100 µl sterile water. Add 1X PBS to the desired protein concentration. |
| Formulation | Lyophilized from 0.2μm-filtered solution in PBS. |
| Other Product Data |
Non-lytic: Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC). |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
This product should be used as the control protein for activity tests of fusion proteins including human target proteins and human IgG-Fc domains.
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