Fc (human) IgG1 Control (rec.) (non-lytic)

CHF 380.00
In stock
CHI-HF-220IG1-C100100 µgCHF 380.00
More Information
Product Details
Product Type Protein
Properties
Source/Host HEK 293 cells
Sequence

Human IgG Fc region (aa 100-330) containing the hinge sequence.

Crossreactivity Human
MW ~25-35kDa (SDS-PAGE)
Purity ≥95% (SDS-PAGE)
Endotoxin Content <1EU/mg purified protein (LAL test; Lonza).
Reconstitution Reconstitute with 100 µl sterile water. Add 1X PBS to the desired protein concentration.
Formulation Lyophilized from 0.2μm-filtered solution in PBS.
Other Product Data

Non-lytic: Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

This product should be used as the control protein for activity tests of fusion proteins including human target proteins and human IgG-Fc domains.

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