IL-1β (human) (rec.) (His)
|Sequence||Human IL-1β (aa 117-269) is fused at the C-terminus to a His-tag.|
|Endotoxin Content||<0.1EU/μg protein (LAL test; Lonza).|
|Reconstitution||Reconstituted in sterile H2O not less than 100μg/ml, which can then be further diluted in other aqueous solutions.|
|Formulation||Lyophilized from a concentrated sterile solution containing 50mM Tris-Hcl buffer (pH 8.0) and 100mM NaCl.|
|Other Product Data||NCBI reference NP_000567.1: IL-1β (human)|
|Declaration||Manufactured by Chimerigen.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Handling Advice||Avoid freeze/thaw cycles.|
Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
|Product Specification Sheet|
IL-1β is produced by activated macrophages. IL-1β stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1β belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1β in most situations requires the inflammasome complex to be cleaved and secreted.