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Chimerigen
IL-1β (human) (rec.) (His)
250
CHF
CHF 250.00
In stock
CHI-HR-20001B-C01010 µgCHF 250.00
CHI-HR-20001B-C05050 µgCHF 720.00
| Product Details | |
|---|---|
| Synonyms | Interleukin-1β IL-1F2 |
| Product Type | Protein |
| Properties | |
| Source/Host | E. coli |
| Sequence | Human IL-1β (aa 117-269) is fused at the C-terminus to a His-tag. |
| Crossreactivity | Human |
| Purity | ≥98% (SDS-PAGE) |
| Endotoxin Content | <0.1EU/μg protein (LAL test; Lonza). |
| Reconstitution | Reconstituted in sterile H2O not less than 100μg/ml, which can then be further diluted in other aqueous solutions. |
| Formulation | Lyophilized from a concentrated sterile solution containing 50mM Tris-Hcl buffer (pH 8.0) and 100mM NaCl. |
| Other Product Data | NCBI reference NP_000567.1: IL-1β (human) |
| Declaration | Manufactured by Chimerigen. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
IL-1β is produced by activated macrophages. IL-1β stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1β belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1β in most situations requires the inflammasome complex to be cleaved and secreted.
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