IL-2 (rat) (recombinant protein) (His)

Specifications / Handling

More Information
Product Details
Synonyms	Interleukin-2; Aldesleukin
Product Type	Protein
Properties
Source/Host	E. coli
Sequence	Rat IL-2 (aa 21-155) is fused at the C-terminus to a His-tag.
Crossreactivity	Rat
Purity	≥95% (SDS-PAGE)
Endotoxin Content	<1EU/μg protein (LAL test; Lonza).
Reconstitution	Reconstituted in sterile H₂O not less than 100μg/ml, which can then be further diluted in other aqueous solutions.
Formulation	Lyophilized from 0.2μm-filtered solution in PBS (pH 7.4).
Other Product Data	NCBI reference NP_446288.1: IL-2 rat)
Declaration	Manufactured by Chimerigen.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-γ and TNF-α and -β. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.

Call	+41 61 926 6040
Fax	+41 61 926 6049

IL-2 (rat) (rec.) (His)