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eTOPIX_New Sensitive ELISA Kits for Metabolic Diseases Research – Sent on 27 January 2021
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| eTOPIX Product Highlights - 27 January 2021 | www.adipogen.com | |||||||||||||||||||||||||||||||||||||||||||||||||
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 The "Hunger Factor" ACBP A NEW & Sensitive Biomarker for Obesity Research |
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Recent studies show that Acyl-CoA-binding Protein [ACBP] levels correlate with human body mass index (BMI). Increasing ACBP levels in mice trigger lipogenesis, food intake and weight gain and neutralization of ACBP increases lipolysis, reduces food intake post-starvation and causes weight loss in mice. Obese patients exhibit elevated plasma levels of ACBP, while a reduction in the ACBP mRNA and ACBP plasma concentration is observed in these patients after a substantial weight loss. ACBP might be useful for the prevention or treatment of obesity and metabolic syndrome diseases.  AdipoGen Life Sciences' Acyl-CoA-binding Protein (human) ELISA Kit (Prod. No. AG-45B-0019) is a sensitive (30pg/ml) colorimetric sandwich immunoassay that detects human ACBP in serum, plasma and cell culture supernatant. It does not detect mouse ACBP. Figure: Secretion of human ACBP during induction of autophagy is measured using the Acyl-CoA-binding Protein (human) ELISA Kit (Prod. No. AG-45B-0019). Method: Human embryonic kidney (HEK 293) (A) and B lymphoblast SKW 6.4 (B) cell lines are treated for 24 hours with different concentrations of the autophagy inducer Everolimus (Prod. No. AG-CN2-0520). Supernatants are collected, diluted and tested using the Acyl-CoA-binding Protein (human) ELISA Kit (Prod. No. AG-45B-0019).  Related other ACBP Reagents!
Other STANDARD ELISAs for Metabolic Diseases Research!
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