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RevMab
anti-Polyethylene Glycol (methoxy group), Rabbit Monoclonal (RM105) (Biotin)
600
CHF
CHF 600.00
In stock
REV-31-1008-02-C05050 µgCHF 600.00
Figure 1: Immunohistochemistry of mouse liver and kidney using 0.5ug/mL of RevMAb anti-PEG Clone RM105 biotin conjugate, followed by an HRP conjugated streptavidin. The mouse was injected with PEG-BSA or BSA 3 hours before sampling.
| Product Details | |
|---|---|
| Synonyms | PEG |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM105 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | KLH-PEG with terminal methoxy group. |
| Label/Conjugates | Biotin |
| Application |
ELISA: 0.02 µg/ml-0.5 µg/ml Immunohistochemistry (IHC): 0.5 µg/ml-2 µg/ml Western Blot (WB) : 0.1 µg/ml-1 µg/ml |
| Crossreactivity | All |
| Specificity | This antibody reacts to the methoxy group of Polyethylene glycol (PEG). It is specific for methoxypoly(ethylene glycol). |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | 1 mg/ml |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | N/A |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Polyethylene glycol (PEG) is a nonbiodegradable hydrophilic polymer widely used in biomedical applications. It has good biocompatibility, is nonimmunogenic and is resistant to protein adsorption. It helps in the purification and crystal growth of proteins and nucleic acids. PEGylation is the act of covalently coupling a PEG structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEGylated protein. The covalent attachment of PEG (PEGylation) is commonly used to modify a variety of proteins and drugs. Some of the therapeutical benefits of PEGylated molecules include increased bioavailability, increased blood circulation of the drug, optimized pharmacokinetics, decreased immunogenicity and decreased frequency of administration. Additional benefits of PEGylated molecules include decelerated renal excretion, improved stability towards proteolysis, increased solubility of the biopharmaceutical in aqueous solutions, increased hydrodynamic radius, reduced immunogenicity and proteolytic cleavage.