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RevMab
anti-Gamma Heavy Chain (human), Rabbit Monoclonal (RM116) (Biotin)
459
CHF
CHF 459.00
In stock
REV-31-1018-02-C05050 µgCHF 459.00
Figure 1: Immunohistochemistry of Human Tonsil using Anti-Gamma Heavy Chain antibody RM116.
| Product Details | |
|---|---|
| Synonyms | Immunoglobulin Gamma HC |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM116 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | Human IgG. |
| Label/Conjugates | Biotin |
| Application |
ELISA: 50ng/well-200ng/well (for Capture) 0.05µg/ml-0.2µg/ml (for Detection) Immunocytochemistry (ICC): 0.5µg/ml-2µg/ml Immunohistochemistry (IHC): 0.5µg/ml-2µg/ml |
| Crossreactivity | Human |
| Specificity | This antibody reacts to the Fc region of all gamma heavy chains of human immunoglobulins, including γ1, γ2, γ3, and γ4. No cross reactivity with other human heavy chains, mouse IgG, rat IgG or goat IgG. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | 1 mg/ml |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | P01857/P01859/P01860/P01861 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Immunoglobulins are heterotetramers composed of 2 immunoglobulin heavy and 2 immunoglobulin light chains. The heavy chain has one variable domain (VH) and three or four constant domains (CH1, CH2, CH3, and CH4). Each light chain exhibits one variable domain (VL) and one constant domain (CL). The variable region (VH and VL) is responsible for antigen recognition and binding while the constant regions (CH and CL) primarily mediate the Ig effector functions, which includes complement activation and Fc Receptor binding.