RevMab

anti-IgE (human), Rabbit Monoclonal (RM122) (Biotin)

CHF 459.00
In stock
REV-31-1024-02-C05050 µgCHF 459.00
More Information
Product Details
Synonyms Immunoglobulin E
Product Type Recombinant Antibody
Properties
Clone RM122
Isotype Rabbit IgG
Source/Host Rabbit
Immunogen/Antigen Human IgE.
Label/Conjugates Biotin
Application ELISA: 10ng/well-100ng/well (for Capture)
0.01µg/ml-0.1µg/ml (for Detection)
Immunocytochemistry (ICC): 0.5µg/ml-2µg/ml
Immunohistochemistry (IHC): 0.5µg/ml-2µg/ml
Crossreactivity Human
Specificity This antibody reacts to human IgE. No cross reactivity with human IgG, IgM, IgD, or IgA.
Purity Protein A purified.
Purity Detail Protein A affinity purified from an animal origin-free culture supernatant.
Concentration 1 mg/ml
Formulation Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Accession Number P01854
Declaration Manufactured by RevMab Biosciences.
Shipping and Handling
Shipping BLUE ICE
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Description

Immunoglobulin E (IgE) is an antibody isotype that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgE's main function is immunity to parasites such as helminths or certain protozoan parasites such as Plasmodium falciparum. IgE may have evolved as a last line of defense to protect against venoms. IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic reactions to drugs, bee stings and antigen preparations used in desensitization immunotherapy. This anti-human secondary antibody has well-characterized specificity for human IgE immunoglobulins and is useful in the detection, sorting or purification of its specified target. In general, secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody.

© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.