RevMab

anti-Monomethyl-Histone H4 (Arg3), Rabbit Monoclonal (RM195)

CHF 251.00
In stock
REV-31-1080-00-C02525 µgCHF 251.00
REV-31-1080-00-C100100 µgCHF 559.00
More Information
Product Details
Synonyms H4 R3me
Product Type Recombinant Antibody
Properties
Clone RM195
Isotype Rabbit IgG
Source/Host Rabbit
Immunogen/Antigen A monomethyl -peptide corresponding to the Monomethyl -Histone H4 (Arg3).
Application

Western Blot: 0.5 µg/ml-2 µg/ml
ELISA: 0.2 µg/ml-1 µg/ml
Multiplex: 0.2 µg/ml-1 µg/ml

Crossreactivity All Vertebrates
Specificity

This antibody reacts to Histone H4 monomethylated at Arginine 3 (R3me1). No cross reactivity with unmodified Arginine 3, asymmetric or symmetric dimethylated Arginine 3, and citrullinated Arginine 3 in Histone H4.

Purity Protein A purified.
Purity Detail Protein A affinity purified from an animal origin-free culture supernatant.
Concentration 1 mg/ml
Formulation Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Isotype Negative Control

Rabbit IgG

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Accession Number P62805
Declaration Manufactured by RevMab Biosciences.
Shipping and Handling
Shipping BLUE ICE
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Description

Histone H4 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H4 is involved with the structure of the nucleosome of the 'beads on a string' organization. Histone proteins are highly post-translationally modified. Covalently bonded modifications include acetylation and methylation of the N-terminal tails. These modifications may alter expression of genes located on DNA associated with its parent histone octamer. Histone H4 is an important protein in the structure and function of chromatin, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes.

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