RevMab

anti-IgG4 Fc (human), Rabbit Monoclonal (RM217)

CHF 459.00
In stock
REV-31-1100-00-C100100 µgCHF 459.00
More Information
Product Details
Synonyms Immunoglobulin G4
Product Type Recombinant Antibody
Properties
Clone RM217
Isotype Rabbit IgG
Source/Host Rabbit
Immunogen/Antigen Peptide corresponding to the Fc region of Human IgG4.
Application

ELISA: 50ng/well-200ng/well (for Capture)
0.05µg/ml-0.2µg/ml (for Detection).

Crossreactivity Human
Specificity

This antibody reacts to the Fc region of human IgG4. No cross reactivity with human IgG1, IgG2, IgG3, IgM, IgA, IgD, IgE, mouse IgG, rat IgG, or goat IgG.

Purity Protein A purified.
Purity Detail Protein A affinity purified from an animal origin-free culture supernatant.
Concentration 1 mg/ml
Formulation Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Isotype Negative Control

Rabbit IgG

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Accession Number P01861
Declaration Manufactured by RevMab Biosciences.
Shipping and Handling
Shipping BLUE ICE
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Description

IgG (Immunoglobulin G) is the most abundant Ig isotype in serum and makes up approximately 75% of all serum Immunoglobulins. In humans, there are four subclasses of IgG with highest serum concentrations of IgG1 followed by IgG2, IgG3 and IgG4. The IgG molecule consists of two heavy and two lights chains (κ or λ) resulting in a molecule with two arms for antigen binding. High levels of IgG antibodies are induced following the initial IgM response in a typical immune response to antigens. Because of its relative abundance and excellent specificity toward antigens, IgG is the principle antibody used in immunological research and clinical diagnostics. Clinically, measured IgG antibody levels are generally considered to be indicative of an individual's immune status to particular pathogens. This anti-human secondary antibody has well-characterized specificity for human IgG4 immunoglobulins Fc region and is useful in the detection, sorting or purification of its specified target. In general, secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody.

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