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RevMab
anti-PSA (human), Rabbit Monoclonal (RM323)
459
CHF
CHF 459.00
In stock
REV-31-1210-00-R100100 µlCHF 459.00
Figure 1: Immunohistochemical staining of formalin fixed and paraffin embedded human prostate cancer tissue section using anti-PSA rabbit monoclonal antibody (Clone RM323) at a 1:1000 dilution.
| Product Details | |
|---|---|
| Synonyms | Prostate Specific Antigen |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM323 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | Native PSA protein purified from human seminal fluid. |
| Application |
Immunohistochemistry (IHC): 1:500-1:1000 dilution |
| Crossreactivity | Human |
| Specificity |
This antibody reacts to native human PSA (Prostate Specific Antigen), including both free (unbound) form and in a complex with ACT (alpha 1-antichymotrypsin). It may react to reduced PSA at a higher concentration. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | N/A |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | P07288 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Prostate-specific antigen (PSA) is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium and is abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.