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RevMab
anti-MART1 (human), Rabbit Monoclonal (RM333)
459
CHF
CHF 459.00
In stock
REV-31-1220-00-R100100 µlCHF 459.00
Figure 1: Immunohistochemical staining of formalin fixed and paraffin embedded human melanoma tissue section using anti-MART1 rabbit monoclonal antibody (Clone RM333) at a 1:1000 dilution.
| Product Details | |
|---|---|
| Synonyms | Melanoma Antigen Recognized by T-cells 1; Antigen LB39-AA; SK29-AA |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM333 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | A peptide corresponding to the N-terminus of human MART1 (Melanoma antigen recognized by T-cells-1). |
| Application |
Immunohistochemistry (IHC): 1:500-1:1000 dilution |
| Crossreactivity | Human |
| Specificity |
This antibody reacts to human MART1 (Melanoma antigen recognized by T-cells-1). |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | N/A |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | Q16655 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
MART1 is involved in melanosome biogenesis by ensuring the stability of GPR143. It plays a vital role in the expression, stability, trafficking and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes. MART1 is found on the surface of melanocytes and is specific for the melanocyte lineage, found in normal skin, the retina and melanocytes, but not in other normal tissues. It is thus useful as a marker for melanocytic tumors (melanomas).