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RevMab
anti-TTF1 (human), Rabbit Monoclonal (RM373)
459
CHF
CHF 459.00
In stock
REV-31-1259-00-R100100 µlCHF 459.00
Figure 1: Immunohistochemical staining of formalin fixed and paraffin embedded human lung cancer tissue section using anti-TTF1 rabbit monoclonal antibody (Clone RM373) at a 1:500 dilution.
| Product Details | |
|---|---|
| Synonyms | Thyroid Transcription Factor 1 |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM373 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | A peptide corresponding to N-terminus of human TTF1 ((Thyroid transcription factor 1) (Homeobox protein Nkx-2.1). |
| Application |
Immunohistochemistry (IHC): 1:500-1:1000 dilution |
| Crossreactivity | Human |
| Specificity |
This antibody reacts to human TTF1 ((Thyroid transcription factor 1) (Homeobox protein Nkx-2.1). It may also react to mouse and rat TTF1, as predicted by immunogen homology. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | N/A |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | P43699 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
TTF-1 (Thyroid Transcription Factor-1; NK2 Homeobox 1; NKX2-1), a member of the homeodomain-containing transcription factor family, activates the expression of selected genes in the thyroid, lung, and brain. TTF-1 is known to play key roles in the control of embryonic development and differentiation. The expression of TTF-1 is restricted to alveolar type II cells. It has been found in all types of lung cancer but is reported frequently in adenocarcinoma. TTF-1 has been shown to be a favor prognostic factor for survival in non-small-cell lung cancer (NSCLC).