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RevMab
anti-Chromogranin A (human), Rabbit Monoclonal (RM385)
459
CHF
CHF 459.00
In stock
REV-31-1271-00-R100100 µlCHF 459.00
Figure 1: Immunohistochemical staining of formalin fixed and paraffin embedded Medullary Thyroid Carcinoma tissue section using anti-Chromogranin A rabbit monoclonal antibody (Clone RM385) at a 1:2500 dilution.
| Product Details | |
|---|---|
| Synonyms | CgA; Pituitary Secretory Protein I |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM385 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | A peptide corresponding to the N-terminus of human Chromogranin A. |
| Application |
Immunohistochemistry (IHC): 1:5000-1:10000 dilution |
| Crossreactivity | Human |
| Specificity |
This antibody reacts to Human Chromogranin A. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | N/A |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | P10645 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.