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RevMab
anti-TOP2a (human), Rabbit Monoclonal (RM394)
459
CHF
CHF 459.00
In stock
REV-31-1280-00-R100100 µlCHF 459.00
Figure 1: Immunohistochemical staining of formalin fixed and paraffin embedded human tonsil tissue section using anti-TOP2A rabbit monoclonal antibody (Clone RM 394) at a 1:100 dilution.
| Product Details | |
|---|---|
| Synonyms | Topoisomerase II alpha |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM394 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | A peptide corresponding to Human TOP2a. |
| Application |
Immunohistochemistry (IHC): 1:100-1:2000 dilution |
| Crossreactivity | Human |
| Specificity |
This antibody reacts to human TOP2a. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | N/A |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | P11388 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Topo II alpha plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2 and M-phases in transformed and developmentally regulated normal cells. Topo II alpha is also implicated in drug resistance of tumor cells.