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RevMab
anti-PAX8 (human), Rabbit Monoclonal (RM436)
459
CHF
CHF 459.00
In stock
REV-31-1324-00-R100100 µlCHF 459.00
Figure 1: Immunohistochemical staining of formalin fixed and paraffin embedded human Kidney tissue section using anti-Paired box protein Pax-8 rabbit monoclonal antibody (Clone RM436) at a 1:400 dilution.
| Product Details | |
|---|---|
| Synonyms | Paired Box Protein Pax-8 |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM436 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | A peptide corresponding to the C-terminus of human PAX8. |
| Application |
Immunohistochemistry (IHC): 1:100-1:400 dilution |
| Crossreactivity | Human |
| Specificity |
RM436 reacts to human Paired box protein Pax-8. It may also react to mouse and rat Paired box protein Pax-8, as predicted by immunogen homology. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | N/A |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | Q06710 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
PAX8 is a member of the paired box family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.