Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
RevMab
anti-INI1 (SNF5/SMARCB1), Rabbit Monoclonal (RM468)
459
CHF
CHF 459.00
In stock
REV-31-1360-00-R100100 µlCHF 459.00
Figure 1: Immunohistochemical staining of formalin fixed and paraffin embedded human tonsil tissue sections using Anti-INI1 antibody (RM468) at 1:100 dilution.
| Product Details | |
|---|---|
| Synonyms | SNF5/SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; BRG1-associated factor 47 (BAF47) |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM468 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | A peptide corresponding to the C-terminus of human INI1 (SNF5/SMARCB1). |
| Application |
IHC: 1:100 - 1:200 WB: 1:1000 - 1:10000 |
| Crossreactivity | Human |
| Specificity |
RM468 reacts to human INI1 (SNF5/SMARCB1). This antibody may also react to mouse or rat INI1, as predicted by immunogen homology. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | 1 mg/ml |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | Q12824 · SNF5_HUMAN |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
INI1 (also known as SNF5 or SMARCB1) is a protein that is involved in the regulation of transcription, replication, and repair of DNA. It is a subunit of the SWI/SNF chromatin remodeling complex, which helps to open up DNA so that genes can be transcribed. INI1 is also involved in the repair of DNA damage, and it can help to prevent cancer cells from developing. Mutations or deletions of the INI1 gene are associated with a number of different cancers, including malignant rhabdoid tumor (MRT), atypical teratoid/rhabdoid tumor (AT/RT), and clear cell sarcoma of the kidney (CCSK).