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RevMab
anti-Cadherin-17 (human), Rabbit Monoclonal (RM529)
As low as
477
CHF
CHF 477.00
In stock
Only %1 left
REV-31-1422-00-R100100 µlCHF 477.00
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Figure 1: Immunohistochemical staining of formalin fixed and paraffin embedded human normal tissue screening, stained with anti-Cadherin-17 rabbit monoclonal antibody clone RM529 at 1:100 dilution.
| Product Details | |
|---|---|
| Synonyms | CDH17; Intestinal Peptide-associated Transporter HPT-1; Liver–Intestine Cadherin; LI-Cadherin |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM529 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | A peptide corresponding to the internal region of human Cadherin-17. |
| Application |
Immunohistochemistry (IHC): 1:100-1:200 dilution Western Blot (WB): 1:1000-1:2000 dilution |
| Crossreactivity | Human |
| Specificity |
This antibody binds to human Cadherin-17. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| Accession Number | Q12864 |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Cadherin-17 is a calcium-dependent cell adhesion molecule belonging to the cadherin superfamily. It is predominantly expressed in the epithelial cells of the gastrointestinal tract and liver, where it helps maintain cell-cell adhesion and epithelial integrity. Unlike classical cadherins, Cadherin-17 lacks a cytoplasmic catenin-binding domain, suggesting a specialized role in intestinal cell organization and signaling. Its overexpression has been observed in several gastrointestinal cancers, making it a useful diagnostic marker and potential therapeutic target.
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