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RevMab
anti-Phosphotyrosine, Rabbit Monoclonal (RM111)
518
CHF
CHF 518.00
In stock
REV-32-1011-00-C100100 µgCHF 518.00
Figure 1: Immunocytochemistry of serum-starved A431 cells nontreated or treated with EGF
| Product Details | |
|---|---|
| Synonyms | pTyr |
| Product Type | Recombinant Antibody |
| Properties | |
| Clone | RM111 |
| Isotype | Rabbit IgG |
| Source/Host | Rabbit |
| Immunogen/Antigen | Phosphotyrosine-BSA conjugate. |
| Application |
Western Blot (WB): 1:1000 -1:5000 dilution |
| Crossreactivity | All |
| Specificity |
This antibody reacts to tyrosine-phosphorylated proteins. No cross reactivity with nonphosphorylated tyrosine, phosphoserine, and phosphorthreonine. |
| Purity | Protein A purified. |
| Purity Detail | Protein A affinity purified from an animal origin-free culture supernatant. |
| Concentration | 1 mg/ml |
| Formulation | Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Accession Number | N/A |
| Declaration | Manufactured by RevMab Biosciences. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Tyrosine is a non-essential amino acid that is used by cells to synthesize proteins. Some of the tyrosine residues can be tagged (at the hydroxyl group) with a phosphate group (phosphorylated) by protein kinases. In its phosphorylated form, tyrosine is called phosphotyrosine. Tyrosine phosphorylation is considered to be one of the key steps in signal transduction and regulation of enzymatic activity. Phosphotyrosine can be detected through specific antibodies.