AS-252424

Specifications / Handling

More Information
Product Details
Synonyms	AS252424
Product Type	Chemical
Properties
Formula	C₁₄H₈FNO₄S
MW	305.3
CAS	900515-16-4
Purity Chemicals	≥95%
Appearance	Solid.
Solubility	Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Declaration	Manufactured by SynKinase.
Other Product Data	Target: PI3K \| Kinase Group: Lipid Kinase \| Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	OYYVWNDMOQPMGE-SDQBBNPISA-N
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

AS-252424 is a potent and selective PI3K inhibitor. It inhibits human recombinant PI3K α, β, γ and δ with IC(50) values of 30, 940, 20,000, and 20,000nM respectively.

Product References

Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma: V. Pomel, et al.; J. Med. Chem. 49, 3857 (2006)

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