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AS-252424 is a potent and selective PI3K inhibitor. It inhibits human recombinant PI3K α, β, γ and δ with IC(50) values of 30, 940, 20,000, and 20,000nM respectively.
Product References
Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma: V. Pomel, et al.; J. Med. Chem. 49, 3857 (2006)