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SynKinase
AS-252424
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| Product Details | |
|---|---|
| Synonyms | AS252424 |
| Product Type | Chemical |
| Properties | |
| Formula | C14H8FNO4S |
| MW | 305.3 |
| CAS | 900515-16-4 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | OYYVWNDMOQPMGE-SDQBBNPISA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
AS-252424 is a potent and selective PI3K inhibitor. It inhibits human recombinant PI3K α, β, γ and δ with IC(50) values of 30, 940, 20,000, and 20,000nM respectively.
Product References
- Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma: V. Pomel, et al.; J. Med. Chem. 49, 3857 (2006)
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