GW-441756

CHF 72.00
In stock
SYN-1044-M0011 mgCHF 72.00
SYN-1044-M0055 mgCHF 120.00
SYN-1044-M01010 mgCHF 138.00
SYN-1044-M05050 mgCHF 545.00
SYN-1044-M100100 mgCHF 988.00
 
More Information
Product Details
Synonyms GW441756
Product Type Chemical
Properties
Formula C17H13N3O
MW 275.3
CAS 504433-23-2
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: TrkA | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key NXNQLECPAXXYTR-LCYFTJDESA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
GW441756 is an orally active, potent and highly selective TrkA tyrosine kinase inhibitor (IC(50) of 2nM). It specifically blocks TrkA-induced cell death in a dose-dependent manner.
Product References
  1. Dorsomorphin stimulates neurite outgrowth in PC12 cells via activation of a protein kinase A-dependent MEK-ERK1/2 signaling pathway: T.A. Kudo, et al.; Genes Cells 16, 1121 (2011)
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