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SynKinase
Masatinib
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CHF 64.00
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SYN-1053-M0011 mgCHF 64.00
SYN-1053-M0055 mgCHF 85.00
SYN-1053-M01010 mgCHF 128.00
SYN-1053-M05050 mgCHF 497.00
SYN-1053-M100100 mgCHF 894.00

Product Details | |
---|---|
Synonyms | AB1010; Masivet |
Product Type | Chemical |
Properties | |
Formula | C28H30N6OS |
MW | 498.7 |
CAS | 790299-79-5 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO or ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: c-Kit, PDGFR and FGFR3 | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | WJEOLQLKVOPQFV-UHFFFAOYSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS |
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Product Specification Sheet | |
Datasheet |
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Description
Masitinib is a potent, orally available protein tyrosine kinase inhibitor targeting c-Kit, PDGFR and FGFR3. It demonstrates activity for Kit and PDGFRα/β with IC(50) values of 200nM, 540nM and 800nM respectively. It shows weak inhibition of ABL and c-Fms.
Product References
- Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT: P. Dubreuil, et al.; PLoS One 4, e7258 (2009)