CHF 64.00
In stock
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More Information
Product Details
Synonyms AB1010; Masivet
Product Type Chemical
Formula C28H30N6OS
MW 498.7
CAS 790299-79-5
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: c-Kit, PDGFR and FGFR3 | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Masitinib is a potent, orally available protein tyrosine kinase inhibitor targeting c-Kit, PDGFR and FGFR3. It demonstrates activity for Kit and PDGFRα/β with IC(50) values of 200nM, 540nM and 800nM respectively. It shows weak inhibition of ABL and c-Fms.
Product References
  1. Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT: P. Dubreuil, et al.; PLoS One 4, e7258 (2009)
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