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SynKinase
Nilotinib
71
CHF
CHF 71.00
In stock
SYN-1057-M0011 mgCHF 71.00
SYN-1057-M0055 mgCHF 99.00
SYN-1057-M01010 mgCHF 142.00
SYN-1057-M05050 mgCHF 213.00
SYN-1057-M100100 mgCHF 298.00
| Product Details | |
|---|---|
| Synonyms | AMN107; Tasigna |
| Product Type | Chemical |
| Properties | |
| Formula | C28H22F3N7O |
| MW | 529.5 |
| CAS | 641571-10-0 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: Abl - PDGFR - BCR | Kinase Group: RTK, PTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | HHZIURLSWUIHRB-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Nilotinib is an orally bio-available aminopyrimidine-derivative Bcr-Abl tyrosine kinase inhibitor (IC(50) <30nM) with anti-neoplastic activity.
Product References
- Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl: E. Weisberg, et al.; Cancer Cell. 7, 129 (2005)
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