PF-04217903

CHF 72.00
In stock
SYN-1060-M0011 mgCHF 72.00
SYN-1060-M0055 mgCHF 132.00
SYN-1060-M01010 mgCHF 192.00
SYN-1060-M05050 mgCHF 539.00
SYN-1060-M100100 mgCHF 988.00
 
More Information
Product Details
Synonyms PF04217903
Product Type Chemical
Properties
Formula C19H16N8O
MW 372.4
CAS 956905-27-4
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: MET | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key PDMUGYOXRHVNMO-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
PF04217903 is a novel orally bio-available, small molecule tyrosine kinase inhibitor with potential anti-neoplastic activity. It is an extremely selective MET inhibitor, with an IC(50) of 4.8nM.
Product References
  1. Sensitivity of selected human tumor models to PF-04217903, a novel selective c-Met kinase inhibitor: H.Y. Zou, et al.; Mol. Cancer Ther. 11, 1036 (2012)
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