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SynKinase
PF-04217903
CHF 0.00
In stock
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| Product Details | |
|---|---|
| Synonyms | PF04217903 |
| Product Type | Chemical |
| Properties | |
| Formula | C19H16N8O |
| MW | 372.4 |
| CAS | 956905-27-4 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: MET | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | PDMUGYOXRHVNMO-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
PF04217903 is a novel orally bio-available, small molecule tyrosine kinase inhibitor with potential anti-neoplastic activity. It is an extremely selective MET inhibitor, with an IC(50) of 4.8nM.
Product References
- Sensitivity of selected human tumor models to PF-04217903, a novel selective c-Met kinase inhibitor: H.Y. Zou, et al.; Mol. Cancer Ther. 11, 1036 (2012)
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