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SynKinase
PIK-90
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CHF 71.00
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Product Details | |
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Synonyms | PIK90 |
Product Type | Chemical |
Properties | |
Formula | C18H17N5O3 |
MW | 351.4 |
CAS | 677338-12-4 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Slightly soluble (<1mg/ml) in DMSO or ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | ZJAVHOMVDCMAMF-UHFFFAOYSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS |
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Product Specification Sheet | |
Datasheet |
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Description
PIK-90 is a potent PI3K inhibitor with IC(50) values of 11, 18, and 58nM for p110α, γ and δ isoforms respectively. It has an IC(50) of 350nM for the p110β isoform. It also has low mTOR activity.
Product References
- A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling: Z.A. Knight, et al.; Cell 125, 733 (2006)