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SynKinase
PIK-90
As low as
71
CHF
CHF 71.00
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| Product Details | |
|---|---|
| Synonyms | PIK90 |
| Product Type | Chemical |
| Properties | |
| Formula | C18H17N5O3 |
| MW | 351.4 |
| CAS | 677338-12-4 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Slightly soluble (<1mg/ml) in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | ZJAVHOMVDCMAMF-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
PIK-90 is a potent PI3K inhibitor with IC(50) values of 11, 18, and 58nM for p110α, γ and δ isoforms respectively. It has an IC(50) of 350nM for the p110β isoform. It also has low mTOR activity.
Product References
- A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling: Z.A. Knight, et al.; Cell 125, 733 (2006)
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