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SynKinase
SD-169
71
CHF
CHF 71.00
In stock
SYN-1079-M0011 mgCHF 71.00
SYN-1079-M0055 mgCHF 92.00
SYN-1079-M01010 mgCHF 106.00
SYN-1079-M05050 mgCHF 341.00
SYN-1079-M100100 mgCHF 497.00
| Product Details | |
|---|---|
| Synonyms | SD169 |
| Product Type | Chemical |
| Properties | |
| Formula | C9H8N2O |
| MW | 160.2 |
| CAS | 1670-87-7 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: MAPK - p38 | Kinase Group: CMGC | Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | GQMYQEAXTITUAE-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
SD169 is an orally available, ATP-competitive, isoenzyme-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. It is 38 times more potent against p38α MAP kinase (IC(50) of 3.2nM) over p38β MAP kinase (IC(50) of 122nM).
Product References
- Preventive and therapeutic potential of p38 alpha-selective mitogen-activated protein kinase inhibitor in nonobese diabetic mice with type 1 diabetes: S. Medicherla, et al.; J. Pharmacol. Exp. Ther. 318, 99 (2006)