SD-169

CHF 60.00
In stock
SYN-1079-M0011 mgCHF 60.00
SYN-1079-M0055 mgCHF 78.00
SYN-1079-M01010 mgCHF 90.00
SYN-1079-M05050 mgCHF 287.00
SYN-1079-M100100 mgCHF 419.00
 
More Information
Product Details
Synonyms SD169
Product Type Chemical
Properties
Formula C9H8N2O
MW 160.2
CAS 1670-87-7
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: MAPK - p38 | Kinase Group: CMGC | Substrate: Serine-Threonine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key GQMYQEAXTITUAE-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
SD169 is an orally available, ATP-competitive, isoenzyme-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. It is 38 times more potent against p38α MAP kinase (IC(50) of 3.2nM) over p38β MAP kinase (IC(50) of 122nM).
Product References
  1. Preventive and therapeutic potential of p38 alpha-selective mitogen-activated protein kinase inhibitor in nonobese diabetic mice with type 1 diabetes: S. Medicherla, et al.; J. Pharmacol. Exp. Ther. 318, 99 (2006)
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