TGX-221

CHF 78.00
In stock
SYN-1089-M0011 mgCHF 78.00
SYN-1089-M0055 mgCHF 126.00
SYN-1089-M01010 mgCHF 209.00
SYN-1089-M05050 mgCHF 646.00
SYN-1089-M100100 mgCHF 1'023.00
 
More Information
Product Details
Synonyms TGX221
Product Type Chemical
Properties
Formula C21H24N4O2
MW 364.5
CAS 663619-89-4
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key CPRAGQJXBLMUEL-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
TGX221 is a potent, cell permeable ATP-competitive inhibitor of PI3K, with selectivity for the p110β isoform (IC(50) of 50nM).
Product References
  1. Advantages of a selective beta-isoform phosphoinositide 3-kinase antagonist, an anti-thrombotic agent devoid of other cardiovascular actions in the rat: S.A. Sturgeon, et al.; Eur. J. Pharmacol. 587, 209 (2008)
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