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NVP-BGJ398
85
CHF
CHF 85.00
In stock
SYN-1152-M0011 mgCHF 85.00
SYN-1152-M0055 mgCHF 149.00
SYN-1152-M01010 mgCHF 234.00
SYN-1152-M05050 mgCHF 546.00
SYN-1152-M100100 mgCHF 759.00
| Product Details | |
|---|---|
| Synonyms | NVPBGJ398 |
| Product Type | Chemical |
| Properties | |
| Formula | C26H31Cl2N7O3 |
| MW | 560.5 |
| CAS | 872511-34-7 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: FGFR | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | QADPYRIHXKWUSV-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
NVP-BGJ398 inhibits FGFR-WT, FGFR2-WT, FGFR3-K650E, FGFR3-S249C and FGFR4-WT with IC(50) values of 4.6, 4.9, 5, 5 and 168nM, respectively.
Product References
- Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase: V. Guagnano, et al.; J. Med. Chem. 54, 7066 (2011)
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