NVP-BGJ398

CHF 72.00
In stock
SYN-1152-M0011 mgCHF 72.00
SYN-1152-M0055 mgCHF 126.00
SYN-1152-M01010 mgCHF 198.00
SYN-1152-M05050 mgCHF 461.00
SYN-1152-M100100 mgCHF 640.00
 
More Information
Product Details
Synonyms NVPBGJ398
Product Type Chemical
Properties
Formula C26H31Cl2N7O3
MW 560.5
CAS 872511-34-7
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: FGFR | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key QADPYRIHXKWUSV-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
NVP-BGJ398 inhibits FGFR-WT, FGFR2-WT, FGFR3-K650E, FGFR3-S249C and FGFR4-WT with IC(50) values of 4.6, 4.9, 5, 5 and 168nM, respectively.
Product References
  1. Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase: V. Guagnano, et al.; J. Med. Chem. 54, 7066 (2011)
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