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NVP-BGJ398
72
CHF
CHF 72.00
In stock
SYN-1152-M0011 mgCHF 72.00
SYN-1152-M0055 mgCHF 126.00
SYN-1152-M01010 mgCHF 198.00
SYN-1152-M05050 mgCHF 461.00
SYN-1152-M100100 mgCHF 640.00

Product Details | |
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Synonyms | NVPBGJ398 |
Product Type | Chemical |
Properties | |
Formula | C26H31Cl2N7O3 |
MW | 560.5 |
CAS | 872511-34-7 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO or ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: FGFR | Kinase Group: RTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | QADPYRIHXKWUSV-UHFFFAOYSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS |
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Product Specification Sheet | |
Datasheet |
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NVP-BGJ398 inhibits FGFR-WT, FGFR2-WT, FGFR3-K650E, FGFR3-S249C and FGFR4-WT with IC(50) values of 4.6, 4.9, 5, 5 and 168nM, respectively.
Product References
- Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase: V. Guagnano, et al.; J. Med. Chem. 54, 7066 (2011)