PLX4032

CHF 60.00
In stock
SYN-1161-M0011 mgCHF 60.00
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More Information
Product Details
Synonyms Vemurafenib; RG7204; Zelboraf; RO5185426
Product Type Chemical
Properties
Formula C23H18ClF2N3O3S
MW 489.9
CAS 918504-65-1
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: Raf | Kinase Group: TKL | Substrate: Serine-Threonine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key GPXBXXGIAQBQNI-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
PLX4032 (Vemurafenib, RG7204, Zelboraf, RO5185426) is a novel and potent inhibitor of B-RafV600E with an IC(50) of 31nM.
Product References
  1. BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells: E. Sala, et al.; Mol. Cancer Res. 6, 751 (2008)
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