SYN-1164-M0011 mgCHF 234.00
SYN-1164-M0055 mgCHF 390.00
SYN-1164-M01010 mgCHF 610.00
|Solubility||Soluble in DMSO or ethanol.|
|Declaration||Manufactured by SynKinase.|
|Other Product Data||
Target: BTK | Kinase Group: PTK | Substrate: Tyrosine
Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
CGI1746 was identified as a selective and potent ATP-competitive BTK inhibitor with an IC(50) of 1.9nM. It is specific for BTK, with around 1000-fold selectivity over Tec and Src family kinases.
- Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis: J.A. Di Paolo, et al.; Nat. Chem. Biol. 7, 41 (2011)