CHF 85.00
In stock
SYN-1166-M0011 mgCHF 85.00
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Product Details
Synonyms AZD8055; CCG168
Product Type Chemical
Formula C25H31N5O4
MW 465.5
CAS 1009298-09-2
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: mTOR | Kinase Group: Atypical (PIKK) | Substrate: Serine-Threonine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
AZD8055 is a novel ATP-competitive inhibitor of mTOR kinase activity with an IC(50) of 0.8nM. It shows excellent selectivity (~1,000-fold) against all class I phosphatidylinositol 3-kinase (PI3K) isoforms and other members of the PI3K-like kinase family.
Product References
  1. Allosteric and ATP-competitive kinase inhibitors of mTOR for cancer treatment: C. Garcia-Echeverria; Bioorg. Med. Chem. Lett. 20, 4308 (2010)
  2. Optimization of potent and selective dual mTORC1 and mTORC2 inhibitors: the discovery of AZD8055 and AZD2014: K.G. Pike, et al.; Bioorg. Med. Chem. Lett. 23, 1212 (2013)
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