Regorafenib

CHF 96.00
In stock
SYN-1169-M0011 mgCHF 96.00
SYN-1169-M0055 mgCHF 156.00
SYN-1169-M01010 mgCHF 239.00
SYN-1169-M05050 mgCHF 778.00
SYN-1169-M100100 mgCHF 1'251.00
 
More Information
Product Details
Synonyms BAY-73-4506
Product Type Chemical
Properties
Formula C21H15ClF4N4O3
MW 482.8
CAS 755037-03-7
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO or ethanol.
Declaration Manufactured by SynKinase.
Other Product Data Target: VEGFR | Kinase Group: RTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key FNHKPVJBJVTLMP-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR, Kit, RET and Raf-1 with IC(50) values of 13, 4.2, 46, 22, 7, 1.5 and 2.5nM, respectively.
Product References
  1. Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity: S.M. Wilhelm, et al.; Int. J. Cancer 129, 245 (2011)
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