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SynKinase
XL388
CHF 0.00
In stock
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| Product Details | |
|---|---|
| Synonyms | XL-388 |
| Product Type | Chemical |
| Properties | |
| Formula | C23H22FN3O4S |
| MW | 455.5 |
| CAS | 1251156-08-7 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: Chk1 | Kinase Group: CAMK | Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | LNFBAYSBVQBKFR-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
XL388 is a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR) with an IC(50) of 9.9nM.
Product References
- Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR): C.S. Takeuchi, et al.; J. Med. Chem. 56, 2218 (2013)