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SynKinase
MPI-0479605 hydrochloride
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| Product Details | |
|---|---|
| Synonyms | MPI0479605 |
| Product Type | Chemical |
| Properties | |
| Formula | C22H29N7O . HCl |
| MW | 407.5 . 36.5 |
| CAS | 1246529-32-7 (free base) |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: MEK - MEK5 | Kinase Group: STE | Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | BYBIFMLUJUNGNX-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
MPI-0479605 inhibits TTK kinase activity in vitro with an IC(50) of 4nM.
Product References
- Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1: K.D. Tardif, et al.; Mol. Cancer Ther. 10, 2267 (2011)