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CH4987655
227
CHF
CHF 227.00
In stock
SYN-1188-M0011 mgCHF 227.00
SYN-1188-M0055 mgCHF 593.00
SYN-1188-M01010 mgCHF 856.00
SYN-1188-M05050 mgCHF 2'436.00
SYN-1188-M100100 mgCHF 3'884.00

Product Details | |
---|---|
Synonyms | RO4987655 |
Product Type | Chemical |
Properties | |
Formula | C20H19F3IN3O5 |
MW | 565.3 |
CAS | 874101-00-5 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: MEK | Kinase Group: PTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | FIMYFEGKMOCQKT-UHFFFAOYSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS |
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Product Specification Sheet | |
Datasheet |
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CH4987655 (RO4987655) is an orally active and highly selective small-molecule MEK inhibitor with an in vitro IC(50) of 5.2nM.
Product References
- Safety, tolerability, pharmacokinetics and pharmacodynamics following 4 weeks' treatment with empagliflozin once daily in patients with type 2 diabetes: T. Heise, et al.; Diabetes Obes. Metab. 15, 613 (2013)