CH4987655

CHF 227.00
In stock
SYN-1188-M0011 mgCHF 227.00
SYN-1188-M0055 mgCHF 593.00
SYN-1188-M01010 mgCHF 856.00
SYN-1188-M05050 mgCHF 2'436.00
SYN-1188-M100100 mgCHF 3'884.00
 
More Information
Product Details
Synonyms RO4987655
Product Type Chemical
Properties
Formula C20H19F3IN3O5
MW 565.3
CAS 874101-00-5
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO.
Declaration Manufactured by SynKinase.
Other Product Data Target: MEK | Kinase Group: PTK | Substrate: Tyrosine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key FIMYFEGKMOCQKT-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
CH4987655 (RO4987655) is an orally active and highly selective small-molecule MEK inhibitor with an in vitro IC(50) of 5.2nM.
Product References
  1. Safety, tolerability, pharmacokinetics and pharmacodynamics following 4 weeks' treatment with empagliflozin once daily in patients with type 2 diabetes: T. Heise, et al.; Diabetes Obes. Metab. 15, 613 (2013)
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