Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
CH4987655
227
CHF
CHF 227.00
In stock
SYN-1188-M0011 mgCHF 227.00
SYN-1188-M0055 mgCHF 593.00
SYN-1188-M01010 mgCHF 856.00
SYN-1188-M05050 mgCHF 2'436.00
SYN-1188-M100100 mgCHF 3'884.00
| Product Details | |
|---|---|
| Synonyms | RO4987655 |
| Product Type | Chemical |
| Properties | |
| Formula | C20H19F3IN3O5 |
| MW | 565.3 |
| CAS | 874101-00-5 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: MEK | Kinase Group: PTK | Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | FIMYFEGKMOCQKT-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
CH4987655 (RO4987655) is an orally active and highly selective small-molecule MEK inhibitor with an in vitro IC(50) of 5.2nM.
Product References
- Safety, tolerability, pharmacokinetics and pharmacodynamics following 4 weeks' treatment with empagliflozin once daily in patients with type 2 diabetes: T. Heise, et al.; Diabetes Obes. Metab. 15, 613 (2013)
Related Products
