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SynKinase
AZD-8330
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SYN-1195-M0011 mgCHF 142.00
SYN-1195-M0055 mgCHF 241.00
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SYN-1195-M100100 mgINQ
| Product Details | |
|---|---|
| Synonyms | AZD8330 |
| Product Type | Chemical |
| Properties | |
| Formula | C16H17FIN3O4 |
| MW | 461.2 |
| CAS | 869357-68-6 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: MEK1 - MEK2 | Kinase Group: STE | Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | RWEVIPRMPFNTLO-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with an IC(50) of 7nM.
Product References
- A phase I dose-finding, safety and tolerability study of AZD8330 in patients with advanced malignancies: R.B. Cohen, et al.; Eur. J. Cancer 49, 1521 (2013)
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