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SynKinase
TAK-632
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SYN-1203-M0011 mgCHF 99.00
SYN-1203-M0055 mgCHF 170.00
SYN-1203-M01010 mgCHF 241.00
SYN-1203-M05050 mgCHF 922.00
SYN-1203-M100100 mgINQ
| Product Details | |
|---|---|
| Synonyms | TAK632 |
| Product Type | Chemical |
| Properties | |
| Formula | C27H18F4N4O3S |
| MW | 554.5 |
| CAS | 1228591-30-7 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. Slightly soluble (<1mg/ml) in water. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: Raf | Kinase Group: TKL | Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | OJFKUJDRGJSAQB-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
TAK-632 is a potent pan-RAF inhibitor with favorable in vitro activity (BRAF(V600E) IC(50) of 2.4nM.
Product References
- Antitumor activity of the selective pan-RAF inhibitor TAK-632 in BRAF inhibitor-resistant melanoma: A. Nakamura, et al.; Cancer Res. 73, 7043 (2013)
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