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TAK-632
84
CHF
CHF 84.00
In stock
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Product Details | |
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Synonyms | TAK632 |
Product Type | Chemical |
Properties | |
Formula | C27H18F4N4O3S |
MW | 554.5 |
CAS | 1228591-30-7 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO or ethanol. Slightly soluble (<1mg/ml) in water. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: Raf | Kinase Group: TKL | Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | OJFKUJDRGJSAQB-UHFFFAOYSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS |
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Product Specification Sheet | |
Datasheet |
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TAK-632 is a potent pan-RAF inhibitor with favorable in vitro activity (BRAF(V600E) IC(50) of 2.4nM.
Product References
- Antitumor activity of the selective pan-RAF inhibitor TAK-632 in BRAF inhibitor-resistant melanoma: A. Nakamura, et al.; Cancer Res. 73, 7043 (2013)