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SynKinase
VTX-27
CHF 0.00
In stock
SYN-1206-M0011 mgCHF 312.00
SYN-1206-M0055 mgCHF 837.00
SYN-1206-M01010 mgCHF 1'348.00
SYN-1206-M05050 mgINQ
SYN-1206-M100100 mgINQ
Product Details | |
---|---|
Synonyms | VTX27 |
Product Type | Chemical |
Properties | |
Formula | C20H24ClFN6O |
MW | 418.9 |
CAS | 1321924-70-2 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: PKCθ Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | HXWARSZQGAFXJM-MGPUTAFESA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | +4°C |
Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
VTX-27 is a potent and selective inhibitor of the PKCθ enzyme, with over 1000-fold against classical isoforms and over 10000-fold against atypical isoforms.
Product References
- Design and optimization of selective protein kinase C θ (PKCθ) inhibitors for the treatment of autoimmune diseases: J.M. Jimenez, et al.; J. Med. Chem. 56, 1799 (2013)