AdipoGen Life Sciences

anti-GITR (human), mAb (AIT 158D)

As low as CHF 270.00

In stock

Only %1 left

AG-20A-0017-C05050 µgCHF 270.00

AG-20A-0017-C100100 µgCHF 350.00

Figure 1: FACS: Con A-activated human T lymphocytes stained significantly using anti-GITR (human), mAb (AIT 158D) (Prod. No. AG-20A-0017).

Specifications / Handling

More Information
Product Details
Synonyms	Tumor Necrosis Factor Receptor Superfamily Member 18; Activation-inducible TNFR Family Receptor; Glucocorticoid-induced TNFR-related Protein; CD357; TNFRSF18; AITR
Product Type	Monoclonal Antibody
Properties
Clone	AIT 158D
Isotype	Rat IgG2aκ
Immunogen/Antigen	Recombinant human GITR.
Application	ELISA: (direct and indirect: 1:5'000-1:10'000) Flow Cytometry: (1:1'000) Optimal conditions must be determined individually for each application.
Crossreactivity	Human
Specificity	Recognizes human GITR. Does not cross-react with mouse GITR.
Purity Detail	Protein G-affinity purified.
Concentration	1mg/ml
Formulation	Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Isotype Negative Control	Rat IgG2a Isotype Control
RRID	AB_2490099
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-κB activation via the TRAF2/NIK pathway.

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