AdipoGen Life Sciences

anti-ANGPTL7 (human), mAb (Kairos 108-4)

CHF 320.00

In stock

AG-20A-0053-C100100 µgCHF 320.00

Figure 1: Immunohistochemical staining of human tissue using anti-ANGPTL7 (human), mAb (Kairos 108-4) (Prod. No. AG-20A-0053) at 1:100 dilution.
A. Immunoperoxidase staining (cytoplasmic) of formalin-fixed, paraffin-embedded human adrenal gland (200x, brown colour).
B. Isotype control with IgG1 (negative control).

Figure 2: Western blot analysis of human ANGPTL7 using anti-ANGPTL7 (human), mAb (Kairos 108-4) (Prod. No. AG-20A-0053) at 1:2,000 dilution.
1. hANGPTL7 (FLAG^®-tagged).
2. hANGPTL7-FLD protein.
3. hANGPTL7-CCD protein.
4. hVisfatin (FLAG^®-tagged) (negative control).

Specifications / Handling

More Information
Product Details
Synonyms	Angiopoietin-like Protein 7; Cornea-derived Transcript 6 Protein
Product Type	Monoclonal Antibody
Properties
Clone	Kairos 108-4
Isotype	Mouse IgG1κ
Immunogen/Antigen	Recombinant human full length ANGPTL7.
Application	ELISA: (direct or indirect: 1:2'000-1:5'000) Immunohistochemistry: (paraffin sections (1:100)) Western blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions should be determined individually for each application. Note: Tested on recombinant proteins and/or target-protein transfected cell lines in ELISA, Western Blot and/or FACS.
Crossreactivity	Human
Specificity	Recognizes human ANGPTL7. Detects a band of ~45kDa by Western blot. Weakly cross-reacts with human ANGPTL7-CCD.
Purity Detail	Protein G-affinity purified.
Concentration	1mg/ml
Formulation	Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Isotype Negative Control	Mouse IgG1 Isotype Control
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma.

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