AdipoGen Life Sciences

ANGPTL7 (human) (rec.)

CHF 265.00
In stock
AG-40A-0060-C01010 µgCHF 265.00
AG-40A-0060-C05050 µgCHF 790.00
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Product Details
Synonyms Angiopoietin-like Protein 7; Cornea-derived Transcript 6 Protein; CDT6
Product Type Protein
Properties
Source/Host HEK 293 cells
Sequence Human ANGPTL7 (aa 1-346) is fused at the C-terminus to a FLAG®-tag.
Crossreactivity Human
Biological Activity Activates ERK phosphorylation in THP-1 cells.
MW ~45kDa (SDS-PAGE)
Purity ≥90% (SDS-PAGE)
Endotoxin Content <0.1EU/μg purified protein (LAL test; Lonza).
Concentration 0.5 mg/ml
Formulation Liquid. 0.2μm-filtered solution in PBS.
Other Product Data UniProt link O43827: ANGPTL7 (human) [Precursor]
FLAG is a registered trademark of Sigma-Aldrich Co.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
For maximum product recovery after thawing, centrifuge the vial before opening the cap.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

ANGPTL7 (Angiopoietin-like protein 7) is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/β-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma.

Product References
  1. Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors: H.E. Broxmeyer, et al.; Blood Cells Mol. Dis. 48, 25 (2012)
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